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Tag: drug development

CPTR 2017 Workshop: Summaries, Slides, and Videos — Day 4

Welcoming Remarks Marco Schito (Critical Path Institute) Marco Schito kicked off the final day of CPTR’s 2017 Workshop by affirming the essential role of diagnostics in effective TB treatment, and contrasting that importance with a lack of corresponding investment in the field, despite such a compelling value proposition. Schito outlined reasons why diagnostic development has […]

May 17, 2017 Drug Development Events RDST Regulatory Science Research Resources Assay Development biomarkers clinical trials Community Engagement CPTR Workshop 2017 diagnostics drug development drug resistance fluroquinolones hollow fiber model next-generation sequencing ReSeq TB ReseqTB TB-PACTS

CPTR 2017 Workshop: Summaries, Slides, and Videos — Day 3

Welcoming Remarks Jim Gallarda (Bill & Melinda Gates Foundation) Jim Gallarda opened the day’s agenda by reminding participants of the importance of collaboration and that silos often act as the largest impediments to progress in global health. Video     Keynote Address: Learning from the Impact of the Drug-Diagnostic Development Strategy in Oncology Jan Trost […]

May 17, 2017 Drug Development Events RDST Regulatory Science Research Resources Assay Development biomarkers clinical trials Community Engagement CPTR Workshop 2017 diagnostics drug development drug resistance fluroquinolones hollow fiber model next-generation sequencing ReSeq TB ReseqTB TB-PACTS

CPTR 2017 Workshop: Summaries, Slides, and Videos — Day 1

Welcoming Remarks Jan Gheuens (Bill & Melinda Gates Foundation) & Debra Hanna (Critical Path Institute) Jan Gheuens opened the event by reflecting on the growth and progress of the CPTR Initiative, as well as forward to its ongoing work. He stressed that the direction of CPTR is truly determined by those who participate it in, […]

May 17, 2017 Drug Development Events RDST Regulatory Science Research Resources Assay Development biomarkers clinical trials Community Engagement CPTR Workshop 2017 diagnostics drug development drug resistance fluroquinolones next-generation sequencing ReSeq TB ReseqTB TB-PACTS

CPTR 2017 Workshop: Workshop Demos and Breakout Sessions

The 2017 CPTR Workshop included topical breakout sessions on a range of topics, including interactive training demonstrations on several tools developed through CPTR partnerships. Demo: Interactive Tool for Optimal Positioning of Time-to-Positivity Results in Patients with TB The CPTR modeling and simulation team, in partnership with Certara, developed a quantitative model that describes the longitudinal […]

May 16, 2017 Drug Development Events RDST Uncategorized Assay Development biomarkers clinical trials CPTR Workshop 2017 diagnostics drug development ReSeq TB ReseqTB

ReSeqTB Data Platform Available to Public

The Rapid Drug Susceptibility Testing Consortium, coordinated by the Critical Path Institute through the Critical Path to TB Drug Regimens (CPTR) initiative, announces the public launch of the Relational Sequencing TB Data Platform (ReSeqTB). ReSeqTB is a data-sharing platform and analytic visualization tool that can be used to discover, grade, and track key bacterial drug resistance mutations. […]

January 10, 2017 Drug Development RDST Research Resources clinical trials drug development ReSeq TB

TB-PACTS Initiative Accepting Requests for Access

The TB-PACTS initiative represents a collaborative partnership between the Special Programme for Research and Training in Tropical Disease (TDR), the TB Alliance, St. George’s University of London, and Critical Path Institute (C-Path). The TB-PACTS data platform is designed to catalyze and accelerate innovative tuberculosis (TB) research by making aggregated Phase III TB clinical trial data […]

October 24, 2016 Drug Development Partner News Research Resources clinical trials drug development fluroquinolones TB-PACTS

2017 CPTR Annual Workshop to be Held March 20 – 23 in Washington DC

The 2017 Critical Path to TB Drug Regimens (CPTR) Annual Workshop, will be held March 20-23, 2017, in Washington DC. DATE: Monday, March 20 through Thursday, March 23, 2017 LOCATION: Washington, DC – Washington Marriot at Metro Center | 775 12th Street NW | 20005 Engaging panel sessions are being developed to showcase the exciting […]

October 12, 2016 Drug Development Events RDST Regulatory Science Research Resources Assay Development CPTR Workshop 2017 drug development

9th International Workshop on Pharmacology of TB Drugs – October 24th in Liverpool

The 9th edition of the International Workshop on Pharmacology of Tuberculosis Drugs will be held on 24 October 2016 in Liverpool, United Kingdom, preceding the Union World Conference on Lung Health 2016. The aim of this abstract-driven workshop is to make a significant contribution to the optimization of TB treatment, by bringing experts together and […]

October 12, 2016 Drug Development Events clinical trials drug development IUATLD Conference pharmacology

Symposium on TB ReFLECT: An integrated analysis of the fluoroquinolone TB trials – October 27, 2016 – Liverpool

On October 27th, CPTR will co-chair a symposium with the World Health Organization (WHO) at the Union World Conference on Lung Health.  This session will highlight a joint initiative by WHO and CPTR to maximize learnings from recent Phase III fluoroquinolone treatment shortening TB clinical trials through integrated meta-analysis. Presentations and panel discussion will emphasize […]

October 9, 2016 Drug Development Events drug development IUATLD Conference TB-PACTS

CPTR and SIMCYP launch models to evaluate exposure and efficacy of TB drugs in combination

The Critical Path to TB Drug Regimens (CPTR) Initiative and SIMCYP have partnered to develop a TB-specific set of models and compound files to inform the design of first-in-human trials that will simultaneously evaluate the exposure and efficacy of novel anti-TB combination regimens of up to 4 drugs. This collection of models is comprised of: […]

October 1, 2016 Drug Development Partner News clinical trials Disease-Modeling drug development