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2018 Critical Path to TB Drug Regimens (CPTR) Annual Workshop, to be held April 23-25, 2018, in Washington, DC.

Please mark your calendar for the 2018 Critical Path to TB Drug Regimens (CPTR) Annual Workshop.

October 17, 2017 Uncategorized

Summary of CPTR – NIAID 2017 Joint Workshop

On September 11 and 12, CPTR and NIAID held a joint workshop to develop a preclinical roadmap to guide advancement of entirely novel regimens, and consider how the principles of a rigorous, data-driven roadmap can contribute to the development of treatment courses that may include sequential combinations of existing and emerging drugs to lead to shorten […]

October 17, 2017 Drug Development Events animal models biomarkers drug development mouse model

CPTR 2017 Workshop: Summaries, Slides, and Videos — Day 4

Welcoming Remarks Marco Schito (Critical Path Institute) Marco Schito kicked off the final day of CPTR’s 2017 Workshop by affirming the essential role of diagnostics in effective TB treatment, and contrasting that importance with a lack of corresponding investment in the field, despite such a compelling value proposition. Schito outlined reasons why diagnostic development has […]

May 17, 2017 Drug Development Events RDST Regulatory Science Research Resources Assay Development biomarkers clinical trials Community Engagement CPTR Workshop 2017 diagnostics drug development drug resistance fluroquinolones hollow fiber model next-generation sequencing ReSeq TB ReseqTB TB-PACTS

CPTR 2017 Workshop: Summaries, Slides, and Videos — Day 3

Welcoming Remarks Jim Gallarda (Bill & Melinda Gates Foundation) Jim Gallarda opened the day’s agenda by reminding participants of the importance of collaboration and that silos often act as the largest impediments to progress in global health. Video     Keynote Address: Learning from the Impact of the Drug-Diagnostic Development Strategy in Oncology Jan Trost […]

May 17, 2017 Drug Development Events RDST Regulatory Science Research Resources Assay Development biomarkers clinical trials Community Engagement CPTR Workshop 2017 diagnostics drug development drug resistance fluroquinolones hollow fiber model next-generation sequencing ReSeq TB ReseqTB TB-PACTS

CPTR 2017 Workshop: Summaries, Slides, and Videos — Day 2

Welcoming Remarks Mel Spigelman (TB Alliance) Mel Spigelman opened the second day of the workshop by introducing the day’s agenda and drawing attention to the personal stories of TB patients, reinforcing the driving force behind CPTR and all TB research and development efforts. Video   Driving Progress Through Regulatory Innovation – Learnings from Oncology and […]

May 17, 2017 Drug Development Events RDST Regulatory Science Research Resources Uncategorized Assay Development biomarkers clinical trials Community Engagement CPTR Workshop 2017 diagnostics drug resistance fluroquinolones hollow fiber model ReSeq TB TB-PACTS

CPTR 2017 Workshop: Summaries, Slides, and Videos — Day 1

Welcoming Remarks Jan Gheuens (Bill & Melinda Gates Foundation) & Debra Hanna (Critical Path Institute) Jan Gheuens opened the event by reflecting on the growth and progress of the CPTR Initiative, as well as forward to its ongoing work. He stressed that the direction of CPTR is truly determined by those who participate it in, […]

May 17, 2017 Drug Development Events RDST Regulatory Science Research Resources Assay Development biomarkers clinical trials Community Engagement CPTR Workshop 2017 diagnostics drug development drug resistance fluroquinolones next-generation sequencing ReSeq TB ReseqTB TB-PACTS

CPTR 2017 Workshop: Workshop Demos and Breakout Sessions

The 2017 CPTR Workshop included topical breakout sessions on a range of topics, including interactive training demonstrations on several tools developed through CPTR partnerships. Demo: Interactive Tool for Optimal Positioning of Time-to-Positivity Results in Patients with TB The CPTR modeling and simulation team, in partnership with Certara, developed a quantitative model that describes the longitudinal […]

May 16, 2017 Drug Development Events RDST Uncategorized Assay Development biomarkers clinical trials CPTR Workshop 2017 diagnostics drug development ReSeq TB ReseqTB

Critical Path Institute and TGen Forge Partnership to Advance TB Research

C-Path and the Translational Genomics Research Institute (TGen) are excited to announce a new partnership to sequence at least 12,000 tuberculosis (TB) bacteria isolates from around the world.

May 1, 2017 Partner News RDST Assay Development diagnostics drug resistance next-generation sequencing ReSeq TB ReseqTB

ReSeqTB Data Platform Available to Public

The Rapid Drug Susceptibility Testing Consortium, coordinated by the Critical Path Institute through the Critical Path to TB Drug Regimens (CPTR) initiative, announces the public launch of the Relational Sequencing TB Data Platform (ReSeqTB). ReSeqTB is a data-sharing platform and analytic visualization tool that can be used to discover, grade, and track key bacterial drug resistance mutations. […]

January 10, 2017 Drug Development RDST Research Resources clinical trials drug development ReSeq TB

Let’s Make TB History!

I visited South Africa earlier this year to learn more about the progress the country is making in the fight against HIV. I toured health clinics, met with doctors and researchers, and listened to the stories of people living with HIV. Again and again, our conversations turned to an often forgotten disease which is HIV’s […]

November 2, 2016 Uncategorized