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Category: RDST

ReSeqTB Data Platform Available to Public

The Rapid Drug Susceptibility Testing Consortium, coordinated by the Critical Path Institute through the Critical Path to TB Drug Regimens (CPTR) initiative, announces the public launch of the Relational Sequencing TB Data Platform (ReSeqTB). ReSeqTB is a data-sharing platform and analytic visualization tool that can be used to discover, grade, and track key bacterial drug resistance mutations. […]

January 10, 2017 Drug Development RDST Research Resources clinical trials drug development ReSeq TB

2017 CPTR Annual Workshop to be Held March 20 – 23 in Washington DC

The 2017 Critical Path to TB Drug Regimens (CPTR) Annual Workshop, will be held March 20-23, 2017, in Washington DC. DATE: Monday, March 20 through Thursday, March 23, 2017 LOCATION: Washington, DC – Washington Marriot at Metro Center | 775 12th Street NW | 20005 Engaging panel sessions are being developed to showcase the exciting […]

October 12, 2016 Drug Development Events RDST Regulatory Science Research Resources Assay Development CPTR Workshop 2017 drug development

CPTR Workshop 2016: Full Content Day 4

Opening Remarks Speaker: Marco Schito, Critical Path Institute March Schito opened the last day of the CPTR 2016 Workshop recapping the progresses and challenges relating to DST development and summarizing the diagnostic development pathway. Schito shared insight on the future of DST, including the need for new policies to support the work and implementation of […]

May 3, 2016 Drug Development RDST Regulatory Science Research Resources Assay Development clinical trials CPTR Workshop 2016 drug development ReSeq TB

CPTR Workshop 2016: Full Content Day 3

Opening Remarks Speaker: Jim Gallarda, Bill & Melinda Gates Foundation Jim Gallarda set the stage for the day by considering how success in improved diagnostics should be defined, and stressing the need for innovation from both the supply (developers) side and the demand (users, uptake, and implementers) side. Gallarda emphasized that incentives are needed on […]

May 2, 2016 Drug Development RDST Regulatory Science Research Resources Assay Development clinical trials CPTR Workshop 2016 drug development ReSeq TB

CPTR Workshop 2016: Full Content Day 2

Welcoming Remarks Speaker: Mel Spigelman, TB Alliance Mel Spigelman opened the day’s program by reflecting on the changing landscape of TB drug development from a sponsor perspective. Noting that the new drugs themselves are the “beef” of the CPTR initiative, he commented that the current state of TB research has seen the retreat of some […]

May 2, 2016 Drug Development RDST Regulatory Science Research Resources Assay Development clinical trials CPTR Workshop 2016 drug development ReSeq TB

CPTR Workshop 2016: Full Content Day 1

Opening Remarks Speaker: Jan Gheuens, Bill & Melinda Gates Foundation Jan Gheuens opened CPTR’s 2016 Workshop by reminding the audience of the principles and mission of the CPTR Initiative, stressing the urgency of accelerating the development and availability of new TB combination therapies and noting the role of partnership and coordination in achieving the mission. […]

May 2, 2016 Drug Development RDST Regulatory Science Research Resources Assay Development clinical trials Community Engagement CPTR Workshop 2016 drug development

Launch of ReSeqTB Data Platform for CPTR Rapid DST Members and Data Contributors

The Relational Sequencing TB Consortia launched the ReSeqTB Data Platform to data contributors and the Rapid DST Consortia. This novel Platform catalogs extensive genotypic, phenotypic and related metadata from Mycobacterium tuberculosis (M.tb) strains. Open access to standardized and validated data will streamline the development of clinically useful, WHO-endorsed in vitro diagnostic assays for rapid drug susceptibility M.tb tests. […]

December 21, 2015 RDST ReseqTB

World TB Day 2015 Supplement Profiles TB Diagnostic Landscape

Read the supplement to the Journal of Infectious Diseases called “Tuberculosis Diagnostics in 2015: Landscape, Priorities, Needs, and Prospects,” which can be found here. Madhukar Pai and Marco Schito write: “In 2015, tuberculosis remains a major global health problem, and drug-resistant tuberculosis is a growing threat. Although tuberculosis diagnosis in many countries is still reliant on older tools, […]

March 20, 2015 Drug Development RDST