Tiong Xun Ting on Battling MDR-TB

Challenges to diagnosis and treatment


CPTR Data Sharing Tools: TB-PACTS & ReSeqTB

Info about and how to participate in TB-PACTS and ReSeqTB

CPTR: Workshop 2016 Highlights

Washington DC, April 4-7

Christian Lienhardt on TB-PACTS Database

Aggregating and sharing data from multiple clinical trials can yield new insight.


ReSeqTB Data Platform Available to Public

The Rapid Drug Susceptibility Testing Consortium, coordinated by the Critical Path Institute through the Critical Path to TB Drug Regimens (CPTR) initiative, announces the public launch of the Relational Sequencing TB Data Platform (ReSeqTB). ReSeqTB is a data-sharing platform and analytic visualization tool that can be used to discover, grade, and track key bacterial drug resistance mutations. […]

January 10, 2017 Drug Development RDST Research Resources clinical trials drug development ReSeq TB

Let’s Make TB History!

I visited South Africa earlier this year to learn more about the progress the country is making in the fight against HIV. I toured health clinics, met with doctors and researchers, and listened to the stories of people living with HIV. Again and again, our conversations turned to an often forgotten disease which is HIV’s […]

November 2, 2016 Uncategorized

From the Working Groups

Modeling & Simulation Workgroup (M&S-WG) Q4-2015 Update

Working closely with the Data Standards and Integration Workgroup (DSI-WG), the M&S-WG uses aggregated clinical trial data to create robust empirical, mechanistic, and systems biology models and quantitative simulation tools to facilitate TB drug and drug regimen development.

January 22, 2016

Data Standards & Integration Workgroup (DSI-WG) Q4-2015 Update

The DSI-WG provides the information technology (IT) infrastructure to support all CPTR data needs for developing regulatory science tools and methods to enable development of new TB drugs, drug regimens, and diagnostics. Aggregating all relevant data in a secure database for analysis by the CPTR Workgroups and authorized researchers is a key focus for this […]

January 22, 2016

Pre-Clinical and Clinical Sciences Workgroup (PCS-WG) Q4-2015 Update

The PCS-WG is focused on the evidence-based evaluation of translational tools to support effective decision-making and advance new agents from the pre-clinical to clinical development space.  These tools represent innovative approaches to address pre-clinical issues, including pre-clinical in vitro and in vivo efficacy, pre-clinical drug safety, and toxicology, pre-clinical PK/PD analyses involving the use of […]

January 22, 2016
About CPTR

Through partnership, CPTR speeds the development of new and markedly improved drug regimens for tuberculosis.